"... there was not one New York hotel called the Waldorf Astoria but two, and some might say even three. The first Waldorf-Astoria (its name properly hyphenated) resulted from the union of two separate hotels, the Waldorf and the Astoria, built next door to each other on Fifth Avenue during the Gilded Age of the 1890s. Conceived as a civic palace embodying the wealth and position New York City had achieved by the end of the nineteenth century, it revolutionized America’s idea of what a hotel could be and stimulated the building of scores of palatial hotels in cities across the nation emulating its regal ambitions. This first Waldorf-Astoria was demolished in 1929. The second Waldorf Astoria (without the hyphen) is the present one located at Park Avenue and East 49th Street. Opened in 1931, it was the largest, the tallest and the most expensive hotel ever built, not just succeeding its illustrious predecessor, but surpassing it in every way imaginable. Today, more than eighty years after its completion, the Waldorf Astoria remains the epitome of the grand hotel..."
For more on the hotel, check out this article by William Alan Morrison in Gotham: A Blog for Scholars of New York City History.