Collis P. Huntington House, 1898.

In 1889 railroad magnate Collis Huntington, who had only a few years before married his longtime mistress, Arabella, following the death of his first wife, purchased five plots on 57th Street and Fifth Avenue. Just across the street from the massive George B. Post-designed Vanderbilt mansion, Huntington commissioned the same architect to build a grand home. (The rough and uneducated Collis and his sophisticated but poor-born second wife wanted social acceptance; this house was an effort towards that goal.)

Completed in five years, the large mansion included full plumbing; ten bathrooms; a refrigerator room; an attached complex with massage rooms, a heated pool, and a Turkish bath; and ornate wall and ceiling frescoes. (A writer in the 20th century described the jumbled interior of the mansion as resembling "a wayward railroad station.")

Following the completion of the mansion, Huntington made a poorly played attempt to buy their way into New York's elite. It backfired and while their home might have been on Fifth Avenue among the upper echelon of well-heeled New York, they remained on the outside. Huntington died in 1900 and his wife in 1924 (after amassing an extensive art collection and marrying her husband's nephew). In 1925 and 1926 the house had its contents sold at auction, from Arabella's jewelry to Chippendale chairs owned by George Washington. Soon after the house was demolished.

In 1940 Tiffany & Co. opened their flagship store here in a Cross & Cross-designed modern building.