Completed in 1961, the Equitable Life Assurance Building was designed in the International style by the firm Skidmore, Owings & Merrill (architects of Lever House and the Manufacturers Hanover Trust, among others). With this new building, the Equitable Company moved uptown from its long-held (and disaster-tinged) location at 120 Broadway.

The building includes a 42-story main tower and a 14-story mid-block wing. Rendered in a glass curtain wall with low profile aluminum spandrels, the building appears to have a glassier facade than it truly does. The occupancy of the building was well announced with massive lighted signage at the top floors. Once reading Equitable, the lighted sign now declares UBS the building's major tenant.