General Memorial Hospital, 1917.

This still standing fortresslike French Renaissance building was constructed in 1887 as the New York Cancer Hospital, the first medical facility to focus solely on cancer. The planning and design of the building reflected prevailing ideas about illness, its causes, and treatment on that era. The hospital was funded by, among others, John Jacob Astor III, who wished to refute the stigma of cancer (in the Victorian period, cancer thought to be contagious and a disease of the poor or those with lacking hygiene). The patients were kept in the round towers, as it was believed that germs flourished in corners. The large windows in the circular towers allowed for more light, better ventilation, and a better view of the patients for the medical staff. Given the low survival rate of cancer patients in the early years of cancer research, the building became known as a death trap (with cancer advancement came an improved reputation).

In the 1950s the building became a nursing home, but the operation shut down in 1974 with claims of patient abuse and crumbling facilities. The city designated the building a landmark in 1976, which saved it from demolition over the next few decades as plans were put forth for reuse, but none came to be. All the while the building continued to deteriorate and became a den for drug addicts during New York's roughest years.

Finally, in 2001 a new owner began work on a residential tower on the west side of the lot. September 11th halted work, but in 2002 new loans and Columbia University's purchase of apartments in the new tower turned the tide. The tower was completed and the old hospital was restored and renovated into 17 luxury units. The roofs were fixed, the mortar repointed, and original windows were replicated.